Lab Education
Home » Review Education Modules » Module 1 » Slide 61 Previous | 61 | Next
Review Education Modules
Gaining Efficiencies in Laboratory Workflow
Continuing Education Certification
Nucleic Acid Tests (NAT)

  • Nucleic acid tests (NATs) identify infectious organisms by detecting specific sequences of their genetic material
    • NATs target either DNA or RNA, depending on the particular assay system
  • There are two types of NATs
    1. Probe-based tests
    2. Amplified tests
  • Probe-based tests use a small fragment-labeled DNA that hybridizes (binds) to a target sequence from the organism
  • Amplified tests use a technology that causes a target sequence from the organism to be duplicated many thousands of times
    • Because amplified tests produce billions of copies of a target sequence, their ability to detect trace amounts of material is very high

Previous | 61 | Next

First in a series of educational programs made possible through an unrestricted grant from

GenProbe